Peter Debye, 1884-1966

Dev118943 1879..1884

Chromobodies are intracellular nanoprobes that combine the specificity of antibodies with the convenience of live fluorescence imaging in a flexible, DNA-encoded reagent. Here, we present the first application of this technique to an intact living vertebrate organism. We generated zebrafish lines expressing chromobodies that trace the major cytoskeletal component actin and the cell cycle marker...

Dev105650 1884..1893

During morphogenesis, organs grow to stereotyped sizes, but growth control mechanisms are poorly understood. Here, we measured the signaling dynamics of the morphogen Dpp, one of several Drosophila factors controlling morphogenetic growth, in the developing eye. In this tissue, the Dpp expression domain advances from the posterior to the anterior tissue edge. In front of this moving morphogen s...

Quarter Ending 31st January 1884

JALDA's Interview with Peter Mühlhäusler

Peter Mühlhäusler is the Foundation Professor of Linguistics at the University of Adelaide, and Supernumerary Fellow of Linacre College, Oxford. He has taught at the Technical University of Berlin and in the University of Oxford. He is an active researcher in several areas of linguistics, including ecolinguistics, language planning, and language policy and language contact in the Australian-Pac...

Dmd066084 1966..1970

Emerging evidence indicates that the aryl hydrocarbon receptor (AhR) plays a crucial role in normal physiologic homeostasis. Additionally, aberrant AhR signaling leads to several pathologic states in the lung and liver. Activation of AhR transcriptionally induces phase I (CYP1A) detoxifying enzymes. Although the effects of the classic AhR ligands such as 3-methylcholanthrene and dioxins on phas...